While many are aware of the vibrant poison dart frogs native to the tropics, not many people know that there are actually venomous frogs as well. In this article, we will delve into the deadly world of venomous frogs and discover the secrets of their lethal secretions.

Venomous frogs vs. Poisonous frogs

Many people use the terms “venomous” and “poisonous” interchangeably, but there is a distinct difference between the two. To put it simply, venomous animals deliver their toxic chemicals through a bite or sting, while poisonous animals harbor toxins in their tissues and can harm others just by being touched or ingested. Venomous frogs are relatively rare compared to their poisonous counterparts.

Meet the Venomous Frogs

Although there are thousands of frog species in the world, only two are known to be venomous. Both of these frogs belong to the family Dendrobatidae and are found in Brazil. These venomous frogs are the Greening’s frog (Aparasphenodon brunoi) and Bruno’s casque-headed frog (Corythomantis greeningi).

Greening’s Frog

Aparasphenodon brunoi, commonly known as Greening’s frog, has small spines on its head that can inject venom through its skin. The venom of Greening’s frog is so potent that it is 25 times more toxic than the venom of a pit viper, making it the most venomous frog in the world. Even a small amount of this venom can be lethal to humans.

Bruno’s Casque-headed Frog

Corythomantis greeningi, or Bruno’s casque-headed frog, has an unusual weapon: bony spines protruding from its skull that break through the skin to deliver the venom. While not as toxic as Greening’s frog’s venom, the toxin of Bruno’s casque-headed frog is still highly potent, causing severe pain and muscle contractions.

The Purpose of Venom in Frogs

The primary purpose of the venom in these frogs is for defense. The pain and other symptoms caused by the venom can deter predators from attacking the frogs. These frogs typically display bright colors, indicating their toxic nature to potential predators. The venom also helps the frogs hunt insects for food more efficiently, as its toxic effects can paralyze or kill prey quickly.

The Secret of the Lethal Secretions

Though venomous frogs are rare, studying their secretions can provide valuable insights into the development of new medications and treatments. Scientists have discovered that the toxins of venomous frogs contain unique proteins and peptides, which could potentially be used to develop new medicines for pain relief, blood clotting, and other medical applications.

For example, the venom of Greening’s frog contains a molecule called tetrodotoxin, which is a powerful neurotoxin that can block nerve signals and cause paralysis. Researchers are examining tetrodotoxin as a potential pain reliever, as blocking nerve signals can interrupt the transmission of pain.


Despite their deadly nature, venomous frogs offer a fascinating glimpse into the world of toxins and their applications. By studying these creatures and their unique secretions, scientists can continue to unlock the potential of their venom for new medical treatments and advancements. As it turns out, there is more to venomous frogs than meets the eye, and their lethal secretions may prove valuable in the development of life-saving medicines.


What is the difference between venomous and poisonous frogs?

Venomous frogs deliver their toxic chemicals through a bite or sting, while poisonous frogs contain toxins in their tissues and can harm others by being touched or ingested.

How many venomous frog species are there?

There are currently only two known venomous frog species in the world: Greening’s frog (Aparasphenodon brunoi) and Bruno’s casque-headed frog (Corythomantis greeningi).

What is the purpose of venom in frogs?

The primary purpose of venom in frogs is for defense against predators and to aid in hunting prey more efficiently.

Can venomous frog secretions be useful for medical purposes?

Yes, the venom of these frogs contains unique proteins and peptides that have potential medical applications, such as pain relief and blood clotting treatments.



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